Article-Journal

Polygenic risk scores predict hypertension onset and cardiovascular risk
Although genetic risk scores have been used to predict hypertension, their utility in the clinical setting remains uncertain. Our study …
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Links between gut microbiome composition and fatty liver disease in a large population sample
Fatty liver disease is the most common liver disease in the world. Its connection with the gut microbiome has been known for at least …
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Sex differences in the cardiac effects of early-onset hypertension
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Early onset hypertension is associated with hypertensive end-organ damage already by MidLife
Early onset hypertension confers increased risk for cardiovascular mortality in the community. Whether early onset hypertension also …
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Trajectories of blood pressure elevation preceding hypertension onset: An analysis of the Framingham heart study original cohort
Importance: Given that hypertension remains a leading risk factor for chronic disease globally, there are substantial ongoing efforts …
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Prognosis of prehypertension without progression to hypertension
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Risk for hypertension crosses generations in the community: a multi-generational cohort study
AIMS: Parental hypertension is known to predict high blood pressure (BP) in children. However, the extent to which risk for …
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Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study
Objective To determine the role of early onset versus late onset hypertension as a risk factor for hypertension in offspring and …
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Office, home, and ambulatory blood pressures as predictors of cardiovascular risk
Ambulatory blood pressure (BP) is considered as the gold standard of BP measurement although it has not been shown to be more strongly …
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Outcome-driven thresholds for home blood pressure measurement: international database of home blood pressure in relation to cardiovascular outcome
The lack of outcome-driven operational thresholds limits the clinical application of home blood pressure (BP) measurement. Our …
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