Selected Publications

Hypertension and Atrial Fibrillation: A Frontier Review From the AF-SCREEN International Collaboration
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Integration of polygenic and gut metagenomic risk prediction for common diseases
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Association between butyrate-producing gut bacteria and the risk of infectious disease hospitalisation: results from two observational, population-based microbiome studies
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Gut microbiome and atrial fibrillation—results from a large population-based study
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2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension: Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA)
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Genetic, molecular, and cellular determinants of sex-specific cardiovascular traits
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Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmented gradient boosting
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Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort
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Diabetes status-related differences in risk factors and mediators of heart failure in the general population: results from the MORGAM/BiomarCaRE consortium
BACKGROUND: The risk of heart failure among diabetic individuals is high, even under tight glycemic control. The correlates and …
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Taxonomic signatures of cause-specific mortality risk in human gut microbiome
The collection of fecal material and developments in sequencing technologies have enabled standardised and non-invasive gut microbiome …
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Polygenic risk scores predict hypertension onset and cardiovascular risk
Although genetic risk scores have been used to predict hypertension, their utility in the clinical setting remains uncertain. Our study …
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Links between gut microbiome composition and fatty liver disease in a large population sample
Fatty liver disease is the most common liver disease in the world. Its connection with the gut microbiome has been known for at least …
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Sex differences in the cardiac effects of early-onset hypertension
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Early onset hypertension is associated with hypertensive end-organ damage already by MidLife
Early onset hypertension confers increased risk for cardiovascular mortality in the community. Whether early onset hypertension also …
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Trajectories of blood pressure elevation preceding hypertension onset: An analysis of the Framingham heart study original cohort
Importance: Given that hypertension remains a leading risk factor for chronic disease globally, there are substantial ongoing efforts …
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Prognosis of prehypertension without progression to hypertension
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Risk for hypertension crosses generations in the community: a multi-generational cohort study
AIMS: Parental hypertension is known to predict high blood pressure (BP) in children. However, the extent to which risk for …
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Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study
Objective To determine the role of early onset versus late onset hypertension as a risk factor for hypertension in offspring and …
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Office, home, and ambulatory blood pressures as predictors of cardiovascular risk
Ambulatory blood pressure (BP) is considered as the gold standard of BP measurement although it has not been shown to be more strongly …
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Outcome-driven thresholds for home blood pressure measurement: international database of home blood pressure in relation to cardiovascular outcome
The lack of outcome-driven operational thresholds limits the clinical application of home blood pressure (BP) measurement. Our …
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Home-measured blood pressure is a stronger predictor of cardiovascular risk than office blood pressure: the Finn-Home study
Previous studies with some limitations have provided equivocal results for the prognostic significance of home-measured blood pressure …
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